Immunology MCQs
Immunology MCQs
Answer these 100+ Immunology MCQs and see how sharp is your knowledge of Immunology. Scroll down and let's start!
1: __________ is not a cardinal sign characteristic of inflammation.
A. Impaired use
B. Redness
C. Pain
D. Heat E
E. Swelling
2: Activated cd8 t cells become __________.
A. Helper T cells
B. NK cells
C. Cytotoxic T cells
D. B cells
3: Antibodies are ___ proteins while antigens are ___ proteins.
A. Bacterial; self-produced
B. Self-produced; foreign
C. Self-produced; also self-produced
D. Cancer; bacterial
E. Viral; self-produced
4: Antibody structures are perfectly suited to directly link ______ to ______.
A. Specificity, antigen
B. Antigen, immune cell
C. Antigenic determinants, different
D. T cells, highest antigenicity
5: Cell-mediated immunity is to t cells as antibody-mediated immunity is to ___________.
A. B cells
B. NK cells
C. TH cells
D. T cells
6: Clonal selection of b cells ________.
A. Occurs during fetal development
B. Results in the formation of plasma cells
C. Cannot occur in the presence of antigens
D. Only occurs in the secondary immune response
7: Complement fixation cannot lead to __________.
A. Enhanced inflammation
B. Opsonization
C. Endogenous pyrexia
D. Bacterial phagocytosis
8: Exogenous antigens are processed for immune recognition by ________ cells.
A. Macrophage
B. All nucleated
C. Dendritic
D. Helper T
E. Dendritic and macrophage
9: Histamine is released from the _____ cells
A. Mast cells
B. Th helper cells
C. Tc helper cells
D. B cells
10: Immunological memory accounts for _____.
A. An antigen can provoke production of high levels of specific antibodies
B. Be unable to differentiate and mature T cells
C. The ancient observation that someone who had recovered from the plague could safely care for those newly diseased.
D. Recombination of the segments of the receptor DNA that make up the functional receptor genes of differentiated B cells
11: Membrane attack complex (mac) kills by ________.
A. Has a lag period while B cells proliferate and differentiate into plasma cells
B. Phagocytosis
C. Disrupting the selectively permeability of a bacteria's plasma membrane
D. Can kill cancer cells before the adaptive immune system is activated
12: Most often, antigens are composed of __________.
A. MHC proteins
B. Phagolysosome
C. Macrophages
D. Glycoproteins
13: Proteins on the surface of phagocytes called ________ aid in the detection of pathogen molecules.
A. NOD proteins
B. Lectins and C3 protein
C. Lectins
D. TLRs
E. Both TLRs and NOD proteins
14: T cells of the immune system include _____.
A. CD4, CD8, and plasma cells
B. Cytotoxic and helper cells
C. Plasma, antigen-presenting, and memory cells
D. Lymphocytes, macrophages, and dendritic cells
15: Memory t cells can be up to __________ old.
A. Weeks
B. Days
C. Decades
D. Years
E. Months
16: This variable region gives an antibody ______ for an _______.
A. Specificity, antigen
B. T cells, highest antigenicity
C. Helper T cells
D. Somatic hypermutation
17: When antibodies bind antigens, the clumping of antigens results from _____.
A. The antibody having at least two binding regions
B. Denaturation of the antibodies
C. Bonds between class I and class II MHC molecules
D. Disulfide bridges between the antigens
18: Antibody functions include all of the following except ________.
A. Binding and inactivating chemical toxins released by bacteria or other microorganisms
B. Cross-linking cell-bound antigens on red blood cells when blood types are properly matched
C. Linking soluble antigens together so that they fall out of solution
D. Targeting foreign cells so that complement proteins can cause cellular lysis
19: B cells respond to the initial antigen challenge by ________
A. Reducing its size
B. Immediately producing antigen-specific antibodies
C. Forming of a large number of cells that are unlike the original B cell
D. Producing progeny cells that include plasma cells and memory cells
20: Naturally acquired passive immunity can result from the _____.
A. Injection of vaccine
B. Ingestion of interferon
C. Placental transfer of antibodies
D. Bsorption of pathogens through mucous membranes
21: This medullary region of the lymph node contains primarily ________.
A. Microphages
B. Macrophages
C. Tonsillar crypts
22: White blood cells and ____ carry out innate immune responses
A. Defensive proteins
B. Attecking proteins
C. None
23: When an antigen is bound to a class i mhc molecule, it can stimulate a ________ cell.
A. Helper T
B. NK
C. Plasma
D. Cytotoxic T
24: When an antigen is bound to a class ii mhc protein, it can activate a ________ cell.
A. CD4 T
B. NK
C. Cytotoxic T
D. Suppressor T
E. Plasma
25: A primary immune response is the ______.
A. Coating the surface of microbes, making it easier for other defense cells to phagocytize them
B. Immune response elicited by the first exposure of lymphocytes to a particular antigen
C. The highest concentration of antibodies that occurs after the first exposure to antigen X
D. Results in the production of short-lived effector cells via clonal selection
26: Antibodies are produced and secreted by ______
A. Plasma cells
B. T cells
C. Bone marrow
D. B cells
27: A characteristic symptom of necrotizing fasciitis is that the pain __________.
A. An enzyme breaks the bacteria free from the phagosome
B. Is disproportionate to the appearance of the infection
C. Avoid eating raw fruits and vegetables
D. Patients may be allergic to penicillins
28: Any substance that triggers an immune response in the body is called a(n) ________.
A. Antigen
B. Active immunity
C. Antibody
D. Passive immunity
29: Antigens bound to mhc ii activate __________.
A. Helper B cells
B. Helper T cells
C. Cytokines
30: Antigens that depend on the function of t-helper cells are called __________ antigens.
A. T-dependent
B. T-independent antigens
C. Both A & B
31: Antimicrobial peptides called ________ are secreted in sweat and damage bacteria and fungi.
A. Antibodies
B. Dermcidins
C. TLRs
D. Complement factors
32: ________ exists when the immune system does not respond to a particular antigen.
A. Tolerance
B. Memory
C. None
33: ________ is the capacity to mount a secondary response to the same antigen.
A. Primary response
B. Memory
C. Innate Immunity
D. Affinity
34: Antibodies are __________ produced in response to an antigen.
A. Immune system cells
B. Glycoproteins
C. Proteins
D. Antigens
35: Autoimmune diseases are an example of a(n) ________ response by the immune system.
A. Lack of
B. Overactive
C. Incorrect
D. None of the answers are correct
36: Cd8 markers are to ________ t cells as cd4 markers are to ________ t cells.
A. Cytoxic; helper
B. Suppressor; cytoxic
C. Plasma; NK
D. Helper; suppressor
E. NK; cytoxic
37: Cytotoxic t (tc) cells are like natural killer (nk) cells because they both __________.
A. Secrete interferons
B. Secrete granzymes and perforin
C. Participate in the immune response
D. Participate in innate immunity
E. Secrete tumor necrosis factor (TNF
38: Fever is induced at the systemic level by ________, which is an endogenous pyrogen.
A. CXCL8
B. IL-12
C. IL-6
D. CCL2
39: Helper t-lymphocytes secrete ________ to stimulate the proliferation of b-lymphocytes.
A. Cytokines
B. Hepatitis
C. Rabies
D. Pregnancy
40: Igm is the first class of antibodies to be made during an immune response because ____.
A. B cells producing IgM develop more rapidly than other types
B. IgM is a multifunctional class of antibody
C. The genes for IgM production are the most active ones in a B cell
D. The gene for the mu Fc region is the first to be attached to the variable region gene
41: Il 2 is involved in __________ tc cells
A. Self-stimulation of
B. Clonal deletion of
C. Antigen presentation to
D. Clonal expansion of
42: In an antibody molecule, the __________ region mediates binding to host cells.
A. Fc
B. CD8
C. Anergic
D. None of these
43: Innate immunity and acquired immunity are both _____.
A. Characteristics of all vertebrate animals
B. Characteristics of all invertebrate animals
C. Both A & B
D. None of the above
44: Monoclonal antibodies are used for the diagnosis of all of the following except ________.
A. Juvenile diabetes
B. Hepatitis
C. Rabies
D. Pregnancy
45: Plasma cells ________.
A. Are large so that they can envelope their prey by phagocytosis
B. Have a great deal of rough endoplasmic reticulum to dispose of ingested pathogens
C. Are small so that they slip between endothelial cells of capillaries to fight infection in the surrounding tissues
D. Have a great deal of rough endoplasmic reticulum reflecting the fact that they secrete a tremendous amount of protein (antibody
46: Prostaglandins function to _________ during an immune response.
A. Activate macrophage
B. Activate complement
C. Induce fever by raising the body's temperature
D. Recruit phagocytic cells
47: T lymphocytes are to the _____ as b lymphocytes are to the _____.
A. Thalamus; bone marrow
B. Bone marrow; thymus
C. Bone marrow; thalamus
D. Thymus; bone marrow
48: The eyes and the respiratory tract are both protected against infections by _____.
A. The mucous membranes that cover their surface
B. The secretion of complement proteins
C. The release of slightly acidic secretions
D. The secretion of lysozyme onto their surface
E. Interferons produced by immune cells
49: The helper t-cell clones stimulate antibody production by _____.
A. B cells
B. Complement cells
C. Plasma cells
D. T cells
50: The secondary response in humoral immunity occurs when memory cells bind to ______.
A. Antigens
B. Complement cells
C. Plasma cells
D. T cells
List of Immunology MCQs Multip...
Available in:
Immunology MCQs
Вопросы иммунологии на русском языке
Preguntas de inmunología en español
日本語での免疫学の質問
Domande di immunologia nelle lingue italiane
Questions d'immunologie en langues françaises
Questões de imunologia em línguas portuguesas
Fragen zur Immunologie in deutschen Sprachen
中文（简体）语言的免疫学问题
أسئلة علم المناعة باللغات العربية
Soal imunologi bahasa indonesia
Türk dillerinde immünoloji soruları
